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The Ebola Wars: The best article I’ve seen yet

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The New Yorker has the best article I have read yet on the Ebola outbreak. Finally we get human story and details of how this outbreak started and spread, along with the outstanding heroic efforts of those on the front line. The article has details on everything, the genetics, the virology, the story of escalating fear as health workers started to get infected, and the hard decisions.

Who would get doses of ZMAPP, and which other experimental therapies would be tried? ZMAPP is the genetically engineered copy of antibodies against Ebola, and it does appear to be useful, even though it has not been properly tested. Kent Brantly, the US doctor who contracted Ebola, improved within hours of receiving ZMAPP. His recovery was so fast his medical staff wondered if it were possible, but his colleague Nancy Writebol did not show the same progress.

Know thy enemy: only six proteins and one line of code, yet so incredibly deadly. The virus is not one virus, but a swarm of particles — an evolving population.

Since Ebola makes errors as it replicates, each genome was like a hand-copied text, and detectable differences would emerge among the genomes; there isn’t [...]


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